2022年Original Article

  • 2022)
    • Nishiwaki S, Watanabe S, Yoneda F, Tanaka M, Aizawa T, Yamagami S, Komasa A, Kawaji T, Yoshizawa T,Kohjitani H, MorimotoT, Kimura T, Shizuta S.  , Impact of catheter ablation on functional tricuspid regurgitation in patients with atrial fibrillation.  , Journal of Interventional Cardiac Electrophysiology ,1–13 (2022) ,  2022/12/13 , doi:10.1007/s10840-022-01410-x.
    • Nishiwaki S, Naka M, Morinaga A, Yoneda F, Tanaka M, Kohjitani H, Shizuta S. , An irregularly irregular supraventricular tachycardia: What is the mechanism? , Journal of Cardiovasc Electrophysiology , 2022/12/13 , https://doi.org/10.1111/jce.15781
    • Mineharu, Y., Nakamura, Y., Sato, N., Kamata, T., Oichi, Y., Fujitani, T., Funaki, T., Okuno, Y., Miyamoto, S., Koizumi, A., & Harada, K. H. (2022). , Increased abundance of Ruminococcus gnavus in gut microbiota is associated with moyamoya disease and non-moyamoya intracranial large artery disease.  , Scientific Reports , 12(1),20244 ,  2022/11/24 , doi:10.1007/s10840-022-01410-x.
    • Yoshizawa T, Ishida S*, Sato T, Ohta M, Honma T, and Terayama K* , Selective Inhibitor Design for Kinase Homologs Using Multiobjective Monte Carlo Tree Search , Journal of Chemical Information and Modeling , 2022/11/22 , https://doi.org/10.1021/acs.jcim.2c00787
    • Kohjitani H, Koda S, Himeno Y, Makiyama T, Yamamoto Y, Yoshinaga D, Wuriyanghai Y, Kashiwa A, Toyoda F, Zhang Y, Amano A,  Noma A&  Kimura T , Gradient-based parameter optimization method to determine membrane ionic current composition in human induced pluripotent stem cell-derived cardiomyocytes , Scientific Reports  , 19110 , 2022/11/9 , https://doi.org/10.1038/s41598-022-23398-0
    • Ueda M, Usami K, Yamao Y, Yamawaki R, Umaba C, Liang N, Nankaku M, Mineharu Y, Honda M, Hitomi T, et al. , Correlation between brain functional connectivity and neurocognitive function in patients with left frontal glioma , Scientific Reports, volume 12,18302 ,  2022/11/8 , https://doi.org/10.1038/s41598-022-22493-6
    • Ohsuga T, Egawa M, Kii M, Ikeda Y, Ueda A, Chigusa Y, Mogami H, Mandai M.,Association between non-anemic iron deficiency in early pregnancy and perinatal mental health: A retrospective pilot study., THE JOURNAL OF Obstet Gynaecol Research ,Nov;48(11):2730-2737 , 2022/11, https://doi.org/10.1111/jog.15397
    • Shimizu S, Kondo J, Onuma K, Ota K, Kamada M, Harada Y, Tanaka Y, Adachi Nakazawa M, Tamada Y, Okuno Y, Kawada K, Obama K, Robert J Coffey, Fujiwara Y, Inoue M , Inhibition of the BMP pathway suppresses tumor growth via downregulation of EGFR in MEK/ERK-dependent colorectal cancer , bio Rxiv , 2022 , doi: https://doi.org/10.1101/2022.11.01.514643
    • Nishi M, Uchino E, Okuno Y, Matoba S. , Robust prognostic prediction model developed with integrated biological markers for acute myocardial infarction. , PLOS ONE , 17(11) , e0277260 , 2022/10/23 , “https://doi.org/10.1371/journal.
      pone.0277260″
    • Iwata H, Hayashi Y, Hasegawa A, Terayama K, Okuno Y, , Classification of scanning electron microscope images of pharmaceutical excipients using deep convolutional neural networks with transfer learning , International Journal of Pharmaceutics , Volume 4 , 100135 , 2022/10/13 , https://doi.org/10.1016/j.ijpx.2022.100135
    • Okamoto Y, Hirano M, Morino K et al. , Early dynamics of chronic myeloid leukemia on nilotinib predicts deep molecular response. , npj Systems Biology and Applications , 8, 39 , 2022/10/13 , https://doi.org/10.1038/s41540-022-00248-3
    • Ryosuke Kojima and Yuji Okamoto , Learning Deep Input-Output Stable Dynamics , Neural Information Processing Systems 2022 , arXiv:2206.13093 , 2022/10/3 , ” https://doi.org/10.48550/arXiv.2206.13093″
    • Ueda A, Watari H, Mandai M, Fukuhara S, Sugitani Y, Ogino K, Kamijima S, Enomoto T. , Incidence of gastrointestinal perforation associated with bevacizumab in combination with neoadjuvant chemotherapy as first-line treatment of advanced ovarian, fallopian tube, or peritoneal cancer: analysis of a Japanese healthcare claims database. , Journal of Gynecolgic Oncology ,  Nov;33(6):e78 ,  2022/9/30 , https://doi.org/10.3802/jgo.2022.33.e78
    • Tabata J, Nakaoku T* (co-first), Araki M, Yoshino R, Kohsaka S, Otsuka A, Ikegami M, Ui A, Kanno S, Miyoshi K, Matsumoto S, Sagae Y, Yasui A, Sekijima M, Mano H, Okuno Y, Okamoto A, Kohno T* , Novel calcium-binding ablating mutations induce constitutive RET activity and drive tumorigenesis , Cancer Research , 2022/9/27, 10.1158/0008-5472.CAN-22-0834
    • Funaki T, Miyakoshi A, Kataoka H, Takahashi JC, Takagi Y, Yoshida K, Kikuchi T, Mineharu Y, Okawa M, Yamao Y, et al. ,Larger Posterior Revascularization Associated with Reduction of Choroidal Anastomosis in Moyamoya Disease: A Quantitative Angiographic Analysis. , American Journal of Neuroradiology , 43,1279–85,2022/9/, DOI: https://doi.org/10.3174/ajnr.A7609
    • Hattori EY, Masuda T, Mineharu Y, Mikami M, Terada Y, Matsui Y, Kubota H, Matsuo H, Hirata M, Kataoka TR, et al , A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice , Communications Biology , 5:939 ,  2022/9/9 , DOI https://doi.org/10.1038/s42003-022-03917-5
    • Kawama K, Fukushima Y, Ikeguchi M, Ohta M, and Yoshidome T , gr Predictor: A Deep Learning Model for Predicting the Hydration Structures around Proteins , Journal of Chemical Information and Modeling , Vol.62, No.18 , 4460–4473 , 2022/9/6 , https://doi.org/10.1021/acs.jcim.2c00987
    • Okamoto M, Kojima R, Ueda A, Suzuki M, Okuno Y , Characterizing eye-gaze positions of people with severe motor dysfunction: Novel scoring metrics using eye-tracking and video analysis , PLOS ONE , 2022/8/31 , https://doi.org/10.1021/acs.jcim.2c00660
    • Iwata H*, Matsuo T, Mamada H, Motomura T, Matsushita M, Fujiwara T, Maeda K, Handa K* , Predicting total drug clearance and volumes of distribution using the machine learning mediated multimodal method through the imputation of various non-clinical data , Journal of chemical information and modeling ,  2022/8/22 , https://doi.org/10.1021/acs.jcim.2c00318
    • Kashiwa A, Makiyama T, Kohjitani H, Maurissen TL, Ishikawa T, Yamamoto Y, Wuriyanghai Y, Gao J, Huang H, Imamura T, Aizawa T, Nishikawa M, Chonabayashi K, Mishima H, Ohno S, Toyoda F, Sato S, Yoshiura KI, Takahashi K, Yoshida Y, Woltjen K, Horie M, Makita N, Kimura T , Disrupted Cav1.2 Selectivity Causes Overlapping Long QT and Brugada Syndrome Phenotypes in CACNA1C-E1115K iPS Cell Model. , Heart Rhythm , S1547-5271(22)02316-5 , 2022/8/22 , DOI:https://doi.org/10.1016/j.hrthm.2022.08.021
    • Takaba K, Watanabe C, Tokuhisa A, Akinaga Y, Ma B, Kanada R, Araki M, Okuno Y, Kawashima Y, Moriwaki H, Kawashita N, Honma T,Fukuzawa K, Tanaka S, Protein–ligand binding affinity prediction of cyclin‐dependent kinase‐2 inhibitors by dynamically averaged fragment molecular orbital‐based interaction energy . , Journal of Computational Chemistry., 43(20), 1362-1371 , 2022/7/30 ,  https://doi.org/10.1002/jcc.26940
    • Takeuchi Y, Mineharu Y, Arakawa Y, Hara M, Oichi Y, Kamata T, Fukuyama K, Yamamoto Y, Yamanaka T, Kakiuchi N, et al. , A novel SREBF1::NACC1 gene fusion in an unclassifiable intracranial tumour , Neuropathology and Applied Neurobiology , 2022/7/28 , https://doi.org/10.1111/nan.12843
    • Tokuhisa A*, Akinaga Y, Terayama K, Okamoto Y, Okuno Y* , Single-Image Super-Resolution Improvement of X-ray Single-Particle Diffraction Images Using a Convolutional Neural Network , Journal of Chemical Information and Modeling , 62, 14,3352–3364 , 2022/7/25 , https://doi.org/10.1021/acs.jcim.2c00660
    • Nojima* S, Ishida S, Terayama K, Matsumoto K, Matsui T, Tahara S, Ohshima K, Kiyokawa H, Kido K, Ukon K, Yoshida S, Mitani T, Doki Y, Mizushima T, Okuno Y, Susaki E, Ueda H, Morii E* , A novel three-dimensional imaging system based on polysaccharide staining for accurate histopathological diagnosis of inflammatory bowel diseases. , Cellular and Molecular Gastroenterology and Hepatology ., 2022/7/11 ,  https://doi.org/10.1016/j.jcmgh.2022.07.001
    • Nishiwaki S, Shizuta S, Tanaka M, Komasa A, Kohjitani H, Kimura T , “A case of preexcitation syndrome showing atypical atrioventricular nodal reentrant tachycardia and orthodromic atrioventricular reciprocating tachycardia with a bystander concealed nodoventricular/ nodofascicular pathway” , Heart Rhythm Case Reports , VOLUME 8, ISSUE 7 , 529-534 , 2022/7/1 , DOI:https://doi.org/10.1016/j.hrcr.2022.05.003
    • 松本 篤幸, 寺山 慧, 奥野 恭史, 深層学習技術を用いたクライオ電子顕微鏡データに潜むタンパク質運動性情報の抽出. , 生物物理, 62(3),193-197 ,2022/6
    • Matsui Y, Mineharu Y, Noguchi Y, Hattori EY, Kubota H, Hirata M, Miyamoto S, Sugiyama H, Arakawa Y, Kamikubo Y., Chlorambucil-conjugated PI-polyamides (Chb-M’), a transcription inhibitor of RUNX family, has an anti-tumor activity against SHH-type medulloblastoma with p53 mutation. , Biochem. Biophys. Res. Commun. ,, 620, 150-157, 2022/6/28, DOI: 10.1016/j.bbrc.2022.06.090
    • Sato K*, Sasaki R, Matsuda R, Nakagawa M, Ekimoto T, Yamane T, Ikeguchi M, Tabata K, Noji H, and Kinbara K* , Supramolecular Mechanosensitive Potassium Channel Formed by Fluorinated Amphiphilic Cyclophane .Journal of the American Chemical Society., 44, 26 , 11802–11809 , 2022/6/21,  https://doi.org/10.1021/jacs.2c04118
    • Hasegawa T, Arakawa Y, Minamiguchi S, Mineharu Y, Nakajima S, Nakajima K, Hirose T, Haga H, Miyamoto S. , Cerebral Tufted Angioma with Gradually Developing Peritumoral Edema: A Case Report , NMC Case Report Journal ,, 9 , 187–192 , 2022/6/21, https://doi.org/10.2176/jns-nmc.2022-0079
    • Natsume A, Arakawa Y, Narita Y, Sugiyama K, Hata N, Muragaki Y, Shinojima N, Kumabe T, Saito R, Motomura K, Mineharu Y, Miyakita Y, Yamasaki F, Matsushita Y, Ichimura K, Ito K, Tachibana M, Kakurai Y, Okamoto N, Asahi T, Nishijima S, Yamaguchi T, Tsubouchi H, Nakamura H, Nishikawa R. , The first-in-human phase I study of a brain penetrant mutant IDH1 inhibitor DS-1001 in patients with recurrent or progressive IDH1-mutant gliomas. Neuro-Oncology ,noac155 ,2022/6/20, https://doi.org/10.3171/2022.4.JNS212505 
    • Tanji M, Mineharu Y, Sakata A, Okuchi S, Fushimi Y, Oishi M, Terada Y, Sano N, Yamao Y, Arakawa Y, et al.,High intratumoral susceptibility signal grade on susceptibility-weighted imaging: a risk factor for hemorrhage after stereotactic biopsy. Journal of Neurosurgery. , 1-8 ,2022/5/13, https://doi.org/10.3171/2022.4.JNS212505 
    • Arakawa Y, Mineharu Y, Uto M, Mizowaki T. , Optimal managements of elderly patients with glioblastoma . Japanese Journal of Clinical Oncology. , hyac075 , 2022/5/12 , https://doi.org/10.1093/jjco/hyac075
    • Seto K, Shimizu J, Masago K, Araki M, Katayama R, Sagae Y, Fujita S, Horio Y, Sasaki E, Kuroda H, Okubo K, Okuno Y, Hida T , Sensitivity to dabrafenib and trametinib treatments in patients with non-small-cell cancer harboring BRAF compound mutations: A pooled analysis of BRAF p.V600E-positive advanced non-small-cell lung cancer . Cancer genetics , 266－267 , 2022/5/11 , DOI: 10.1016/j.cancergen.2022.05.001
    • Nakamura Y, Mineharu Y*, Kamata T, Funaki T, Miyamoto S, Koizumi A, Harada KH , Lack of Association between Seropositivity of Vasculopathy-Related Viruses and Moyamoya Disease . Journal of Stroke and Cerebrovascular Diseases. , 31(7) , 106509 , 2022/4/29 , DOI: 10.1016/j.jstrokecerebrovasdis.2022.106509 
    • Kanada R, Terayama K, Tokuhisa A, Matsumoto S, Okuno Y , Enhanced Conformational Sampling with an Adaptive Coarse-Grained Elastic Network Model Using Short-Time All-Atom Molecular Dynamics . Journal of chemical theory and computation. , 18 (4) , 2062-2074 , 2022/4/18 , https://doi.org/10.1021/acs.jctc.1c01074 
    • Oichi Y, Mineharu Y, Agawa Y, Morimoto T, Funaki T, Hitomi T, Kobayashi H, Todo K, Tani S, Imamura H, Yoshida K, Kataoka H, Koizumi A, Sakai N, Miyamoto S. , Characterization of Moyamoya and Middle Cerebral Artery Diseases by Carotid Canal Diameter and RNF213 p.R4810K Genotype. J Stroke Cerebrovasc Dis. , 14;31(6) , 106481 , 2022/4/14, DOI: 10.1016/j.jstrokecerebrovasdis.2022.106481
    • Kawata M, Fukui A, Mineharu Y, Kikuchi T, Yamao Y, Yamamoto Hattori E, Shiraki A, Mizota T, Furukawa K, Miyamoto S, et al. , A Nationwide Questionnaire Survey on Awake Craniotomy in Japan . Neurologia medico-chirurgica , 2022/3/29, https://doi.org/10.2176/jns-nmc.2021-0290
    • Ishida S , Terayama K , Kojima R, Takasu K, Okuno Y , AI-Driven Synthetic Route Design Incorporated with Retrosynthesis Knowledge , Journal of Chemical Information and Modeling , Vol.62, No.6 , pp.1357–13672022 , 2022/3/8 , https://doi.org/10.1021/acs.jcim.1c01074
    • Huang K, Matsumura H, Zhao Y, Herbig M, Yuan D, Mineharu Y, Harmon J, Findinier J, Yamagishi M, Ohnuki S, Nitta N, Grossman AR, Ohya Y, Mikami H, Isozaki A, Goda K , Deep imaging flow cytometry . Lab on a Chip , 22 , 876-889 , 2022/2/4, https://doi.org/10.1039/D1LC01043C
    • Yamashita H, Arakawa Y, Terada Y, Takeuchi Y, Mineharu Y, Sumiyoshi S, Tokunaga S, Nakajima K, Kawabata N, Tanaka K, et al. , Whole-genome sequencing analysis of an atypical teratoid/rhabdoid tumor in a patient with Phelan-McDermid syndrome: a case report and systematic review. , Brain Tumor Pathol,, 2022/1/24, DOI: 10.1007/s10014-022-00440-7
    • Harada Y,Sato A,Araki M,Matsumoto S,Isaka Y,Sagae Y,Abe T,Aoyagi Y,Sueoka E,Okuno Y,Kimura S & Sueoka-Aragane N, Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test, Cellular Oncology, 2022, https://doi.org/10.1007/s13402-021-00656-3
    • Umaba C,Mineharu Y,Liang N,Mizota T,Yamawaki R,Ueda M,Yamao Y,Nankaku M,Miyamoto S,Matsuda S,Inadomi H,Arakawa Y,Intraoperative hand strength as an indicator of consciousness during awake craniotomy: a prospective, observational study,Scientific Reports,12(1):216., 2022, https://www.nature.com/articles/s41598-021-04026-9