論文

Nojima S#*, Kadoi T, Suzuki A, Kato C, Ishida S, Kido K, Fujita K, Okuno Y, M. Hirokawa, K. Terayama*, Morii E, , Deep-learning-based differential diagnosis of follicular thyroid tumors using histopathological images , Modern Pathology ,100296,2023/7/31, DOI: 10.1016/j.modpat.2023.100296

Aya Nakamura, Ryosuke Kojima, Yuji Okamoto, Eiichiro Uchino, Yohei Mineharu, Yohei Harada, Mayumi Kamada, Manabu Muto, Motoko Yanagita, Yasushi Okuno , A New Deep State-Space Analysis Framework for Patient Latent State Estimation and Classification from EHR Time Series Data. , arXiv:2307.11487 , 2023/7/21 , https://doi.org/10.48550/arXiv.2307.11487

Koyama T, Matsumoto S, Iwata H, Kojima R, Okuno Y. , Improving Compound–Protein Interaction Prediction by Self-Training with Augmenting Negative Samples , Journal of Chemical Information and Modeling , , 63, 15 , 4552–4559 , 2023/7/17 , https://pubs.acs.org/doi/full/10.1021/acs.jcim.3c00269

Hatano N, Kamada M, Kojima R, Okuno Y , Network-based prediction approach for cancer-specific driver missense mutations using a graph neural network. , bioRxiv , 2023/7 , https://doi.org/10.1101/2023.07.05.547896

Shimizu S, Kondo J, Onuma K, Coppo R, Ota K, Kamada M, Harada H, Tanaka Y, Adachi Nakazawa M, Tamada Y, Okuno Y, Kawada K, Kazutaka Obama, Robert J. Coffey, Yoshiyuki Fujiwara, Masahiro Inoue , Inhibition of the bone morphogenetic protein pathway suppresses tumor growth through downregulation of epidermal growth factor receptor in MEK/ERK-dependent colorectal cancer , Cancer Science , 2023/6/25 , doi: 10.1111/cas.15882

Zhu A, Chiba S, Shimizu Y, Kunitake K, Okuno Y, Aoki Y, Yokota T , Ensemble-Learning and Feature Selection Techniques for Enhanced Antisense Oligonucleotide Efficacy Prediction in Exon Skipping . , Pharmaceutics ,15(7) , 1808 , 2023/6/24 , doi.org/10.3390/pharmaceutics15071808

Iwata H, Nakai T, Koyama T, Matsumoto S, Kojima R, Okuno Y*, VGAE-MCTS: a New Molecular Generative Model combining Variational Graph Auto-Encoder and Monte Carlo Tree Search , ChemRxiv , Version 2 , 2023/6/5 , doi.org/10.26434/chemrxiv-2023-q8419-v2

Iwata H, Application of In Silico Technologies for Drug Target Discovery and Pharmacokinetic Analysis , Chemical and Pharmaceutical Bulletin ,2023/6/1 , doi.org/10.1248/cpb.c22-00638

Wang Y, Fushimi Y, Arakawa Y, Shimizu Y, Sano K, Sakata A, Nakajima S, Okuchi S, Hinoda T, Oshima S, Otani S, Ishimori T, Tanji M, Mineharu Y, Yoshida K, & Nakamoto Y , Evaluation of isocitrate dehydrogenase mutation in 2021 world health organization classification grade 3 and 4 glioma adult-type diffuse gliomas with 18F-fluoromisonidazole PET.  , Japanese Journal of Radiology ,2023/5/23 , DOI: 10.1007/s11604-023-01450-x

Gert-Jan Bekker, Araki M, Oshima K, Okuno Y, Kamiya N , Mutual induced-fit mechanism drives binding between intrinsically disordered Bim and cryptic binding site of Bcl-xL , Communications Biology , 6,349 , 2023/3/30 , https://doi.org/10.1038/s42003-023-04720-6