Supporting Information1: Top 7 drugs with the highest multitarget scores against 6 SARS-CoV-2 proteins in MD-based target screening.

Proteins are represented by surface models. The pocket residues are highlighted by yellow.

Nelfinavir mesilate

ADRP

3CLpro

PLpro

Piclidenoson

ADRP

3CLpro

NSP13

NSP16

PLpro

Pevonedistat

ADRP

3CLpro

NSP13

NSP16

PLpro

Famotidine

ADRP

3CLpro

NSP13

NSP16

NSP9

PLpro

Eltrombopag olamine

ADRP

3CLpro

NSP13

NSP16

PLpro

VBY-825

ADRP

3CLpro

NSP16

PLpro

Remdesivir

ADRP

3CLpro

NSP13

PLpro