2010年Original Article

  • 2010)
    • Yabuuchi H, Niijima S, Takematsu H, Ida T, Hirokawa T, Hara T, Ogawa T, Minowa Y, Tsujimoto G, Okuno Y. “Analysis of multiple compound-protein interactions reveals novel bioactive molecules” Molecular Systems Biology. 2011;7:472. Available from: https://dx.doi.org/10.1038%2Fmsb.2011.5
    • Doi, M., Takahashi, Y., Komatsu, R., Yamazaki, F., Yamada, H., Haraguchi, S., Emoto, N., Okuno, Y., Tsujimoto, G., Kanematsu, A., Ogawa, O., Todo, T., Tsutsui, K., van der Horst, G.T., Okamura, H.Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6Nature Medicine, 16, 67-74, 2010. Available from: https://dx.doi.org/10.1038/nm.2061
    • Kusaka M, Katoh-Fukui Y, Ogawa H, Miyabayashi K, Baba T, Shima Y, Sugiyama N, Sugimoto Y, Okuno Y, Kodama R, Iizuka-Kogo A, Senda T, Sasaoka T, Kitamura K, Aizawa S, Morohashi KI. “Abnormal Epithelial Cell Polarity and Ectopic Epidermal Growth Factor Receptor (EGFR) Expression Induced in Emx2 KO Embryonic Gonads” Endocrinology. 2010;151:5893-5904. Available from: https://doi.org/10.1210/en.2010-0915
    • van der Horst E, Peironcely JE, Beukers MW, Lane JR, van Vlijmen HW, Emmerich MT, Okuno Y, Bender A. “A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization” BMC Bioinformatics. 2010;11:316. Available from: https://doi.org/10.1186/1471-2105-11-316
    • Tamba S, Yodoi R, Morimoto K, Inazumi T, Sukeno M, Segi-Nishida E, Okuno Y, Tsujimoto G, Narumiya S, Sugimoto Y. “Expression profiling of cumulus cells reveals functional changes during ovulation and central roles of prostaglandin EP2 receptor in cAMP signaling” Biochimie, 2010;92:665-675. Available from: https://doi.org/10.1016/j.biochi.2010.04.006
    • Hagihara M, Yoneda K, Yabuuchi H, Okuno Y, Nakatani K. “A reverse transcriptase stop assay revealed diverse quadruplex formations in UTRs in mRNA” Bioorg. Med. Chem. Lett., 2010;20:2350-2353. Available from: https://doi.org/10.1016/j.bmcl.2010.01.158
    • Terada N, Shimizu Y, Kamba T, Inoue T, Maeno A, Kobayashi T, Nakamura E, Kamoto T, Kanaji T, Maruyama T, Mikami Y, Toda Y, Matsuoka T, Okuno Y, Tsujimoto G, Narumiya S, Ogawa O. “Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model” Cancer Res. 2010;70:1606-1615. Available from: https://doi.org/10.1158/0008-5472.can-09-2984
    • Takahashi J, Hijikuro I, Kihara T, Murugesh M.G, Fuse S, Kunimoto R, Tsumura Y, Akaike A, Niidome T, Okuno Y, Takahashi T, Sugimoto H. “Design, synthesis, evaluation and QSAR analysis of N(1)-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors” Bioorg. Med. Chem. Lett. 2010;20:1718-1720. Available from: https://doi.org/10.1016/j.bmcl.2010.01.057